Synthesis, α-glucosidase inhibition and antioxidant activity of the 7-carbo-substituted 5-bromo-3-methylindazoles.

doi:10.1016/j.bioorg.2020.103702

Paper

Synthesis, α-glucosidase inhibition and antioxidant activity of the 7-carbo-substituted 5-bromo-3-methylindazoles.

Published Feb 25, 2020 · M. Mphahlele, N. Magwaza, S. Gildenhuys

Bioorganic chemistry

Q1 SJR score

22

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0

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Abstract

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In Vitro Study

Study Snapshot

7-carbo-substituted 5-bromo-3-methylindazoles show significant to moderate -glucosidase inhibition and antioxidant activity, potentially enhancing their anti-cancer effects.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Synthesis, α-glucosidase inhibition and antioxidant activity of the 7-carbo-substituted 5-bromo-3-methylindazoles.

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