2-aminomethyl benzimidazole derivatives had a wide range of biological activities as its antibacterial,anti-inflammatory,sedative,and anticancer.Their synthesis can be easily achieved by amination of 2-chloromethyl benzimidazole.To study their antifungal activity,2-(4-chlorophenyl) aminomethyl benzimidazole was synthesized in 38% overall yield starting from o-phenylenediamine via 2-chloromethyl benzimidazole.

2-(4-chlorophenyl) aminomethyl benzimidazole can be synthesized in 38% overall yield from o-phenylenediamine, offering potential antifungal activity.

Paper

Synthesis of 2-(4-chlorophenyl) Aminomethyl Benzimidazole

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