Paper
Synthesis of 2-aryl-3,3,3-trifluoropropanoic acids using electrochemical carboxylation of (1-bromo-2,2,2-trifluoroethyl)arenes and its application to the synthesis of β,β,β-trifluorinated non-steroidal anti-inflammatory drugs
Published Jan 9, 2010 · Y. Yamauchi, S. Hara, H. Senboku
Tetrahedron
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Abstract
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Electrochemical carboxylation of (1-bromo-2,2,2-trifluoroethyl)arenes efficiently produces 2-aryl-3,3,3-trifluoropropanoic acids, which can be successfully applied to the synthesis of,,-trifluorinated non-
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