Synthesis of 2-aryl-6-methyl-5-nitroquinoline derivatives as potential prodrug systems for reductive activation

doi:10.1016/J.TET.2008.01.043

Paper

Synthesis of 2-aryl-6-methyl-5-nitroquinoline derivatives as potential prodrug systems for reductive activation

Published Mar 17, 2008 · Gavin D. Couch, P. Burke, R. Knox

Tetrahedron

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17

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Abstract

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Study Snapshot

Novel 2-aryl-5-nitroquinolines have been synthesized as potential prodrug systems for bioreductive activation, with potential applications in the treatment of cancer and infectious diseases.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis of 2-aryl-6-methyl-5-nitroquinoline derivatives as potential prodrug systems for reductive activation

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