Synthesis of 2-Chloronicotinic Acid and its Derivatives

Paper

Synthesis of 2-Chloronicotinic Acid and its Derivatives

Published 2003 · Z. Min

Fine Chemical Intermediates

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1

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Abstract

chloronicotinic acid and its derivatives are important intermedicted for drugs and agrochemicals. Their synthetic methods from nicotinic acid were investigated. The results show that these methods are easily industrialized, the raw material easily acquired, and yield of products high. These methods have important practically significance.

Study Snapshot

This study presents an easily industrialized, easily accessible, and high-yielding method for synthesizing 2-chloronicotinic acid and its derivatives, with potential applications in drugs and agrochemicals.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Synthesis of 2-Chloronicotinic Acid and its Derivatives

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References

Citations

Synthesis of 2-Chloronicotinic Acid Derivatives

A rapid synthetic method for 2-morpholinonicotinic acid has been developed, resulting in a 93% yield from three steps, making it useful for the synthesis of medical antibiotics, anti-cardiovascular drugs, and insecticides.