Synthesis of [2H]‐diethoxymethane as a convenient source of a [2H]‐methylene unit

doi:10.1002/JLCR.2580280307

Paper

Synthesis of [2H]‐diethoxymethane as a convenient source of a [2H]‐methylene unit

Published Mar 1, 1990 · J. Hanley, D. Forsyth

Journal of Labelled Compounds and Radiopharmaceuticals

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3

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Abstract

[2H]-Diethoxymethane is prepared in one step from triethylorthoformate. Its usefulness as a precursor to [2H]-formaldehyde is shown by the Diels Alder synthesis of a monolabelled bicyclic amine. The title compound should also be useful in the syntheses of other labelled compounds in which [2H]-formaldehyde is a required reagent.

Study Snapshot

[2H]-diethoxymethane is a convenient precursor to [2H]-formaldehyde, useful in the Diels Alder synthesis of monolabelled bicyclic amines and other labelled compounds.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Synthesis of [2H]‐diethoxymethane as a convenient source of a [2H]‐methylene unit

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