Synthesis of 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as platelet aggregation inhibitors.

doi:10.1016/j.bmcl.2011.11.027

Paper

Synthesis of 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as platelet aggregation inhibitors.

Published 2012 · Xiao Tian, Li-Ying Wang, S. Xia

Bioorganic & medicinal chemistry letters

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14

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0

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Abstract

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In Vitro Study

Study Snapshot

2H-benzo[b][1,4]oxazin-3(4H)-one derivatives effectively inhibit platelet aggregation, with compound 7a showing the most potent inhibitory effect.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis of 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as platelet aggregation inhibitors.

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