Synthesis of new polyfunctional 2-pyrrolidinones from methyl 2-(carboethoxyhydroxymethyl)acrylate

doi:10.1016/J.TETLET.2007.05.122

Paper

DOI: 10.1016/J.TETLET.2007.05.122

Synthesis of new polyfunctional 2-pyrrolidinones from methyl 2-(carboethoxyhydroxymethyl)acrylate

Published Jul 30, 2007 · Jean-François Morizur, L. Mathias

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Abstract

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This study presents a simple, mild, and efficient method for preparing new polyfunctional 2-pyrrolidinone derivatives from methyl 2-(carboethoxyhydroxymethyl)acrylate, with high reactivity upon Michael addition with primary amines.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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