OBJECTIVE To synthesize the compounds of 2-substituted ethyl 2-[1-(pyridine-2-yl)ethoxy] acetate and study its effects for ability of memory in mice.METHODSThe compounds of 2-substituted ethyl 2-[1-(pyridine-2-yl)ethoxy] acetate(5~7) were prepared by using 2-ethylpyridine,through Whol-Ziegler reaction,Williamson reaction and esterification reaction,and its effects for ability of memory in mice were studied by swimming maze test.RESULTSThe 2-morpholinoethyl 2-(1-(pyridin-2-yl)ethoxy) acetate(5) has the effect of improving the ability of memory in mice.

2-substituted ethyl 2-[1-(pyridine-2-yl)ethoxy] acetate improves memory ability in mice when used as a memory enhancer.

Paper

Synthesis of 2-substituted ethyl 2-[1-(pyridine-2-yl)ethoxy] acetate and its effects for ability of memory in mice

References

Citations