Paper
Synthesis of 3,5-disubstituted pyrazoles via cyclocondensation of 1,2-allenic ketones with hydrazines: application to the synthesis of 5-(5-methyl-pyrazol-3-yl)-2′-deoxycytidine
Published Apr 10, 2012 · Shenghai Guo, Jiliang Wang, Dongqiang Guo
RSC Advances
Q1 SJR score
24
Citations
0
Influential Citations
Abstract
An efficient procedure for the synthesis of 3,5-disubstituted pyrazoles has been achieved through cyclocondensation reaction of 1,2-allenic ketones and hydrazines under extremely mild conditions. As an application, this methodology provides a highly efficient route to 5-(5-methyl-pyrazol-3-yl)-2′-deoxycytidine.
Study Snapshot
This study demonstrates a highly efficient method for synthesis of 3,5-disubstituted pyrazoles under mild conditions, providing a route to 5-(5-methyl-pyrazol-3-yl)-2′-deoxycytidine.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
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