3,5-Di- tert -butyl-4-hydroxybenzoic acid was synthesized in 63.7% overall yield by treatment of 2,6-di- tert -butyl-4-methylphenol with bromine in acetic acid to give 3,5-di- tert -butyl-4-hydroxy- benzaldehyde which underwent oxidization by Jones reagent.

3,5-Di-tert-butyl-4-hydroxybenzoic acid can be synthesized in a 63.7% overall yield by treating 2,6-di-tert-butyl-4-methylphenol with bromine in acetic acid, yielding 3,5-di-tert-but

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Synthesis of 3,5-Di-tert-butyl-4-hydroxybenzoic Acid

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