Paper

Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase.

Published Oct 1, 2010 · E. Maccioni, S. Alcaro, F. Orallo

European journal of medicinal chemistry

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Abstract

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In Vitro Study

Study Snapshot

Differently substituted 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives show selective inhibitory activity towards the B isoform of monoamine oxidase, regardless of their heterocyclic ring substitution.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase.

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