Synthesis of new 3-phenyl Substituted Dibenzo-1,4-diazepin-1-one Derivatives

doi:10.3184/174751914X14138073011066

Paper

Synthesis of new 3-phenyl Substituted Dibenzo-1,4-diazepin-1-one Derivatives

Published Nov 1, 2014 · Fang‐Ming Wang, Dan Bao, Ming Wang

Journal of Chemical Research

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Abstract

A new series of 3-phenyl substituted dibenzo-1,4-diazepin-1-one derivatives were synthesised by condensation of 5-phenylcyclohexane-1,3-dione, o-phenylenediamine and benzaldehydes. All the compounds were characterised by IR, MS, 1H NMR and elemental analysis. The crystal structure of 3-phenyl-11-(2-chlorophenyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e] [1,4]diazepin-1-one was determined by X-ray single-crystal diffraction.

Study Snapshot

This study synthesized a new series of 3-phenyl substituted dibenzo-1,4-diazepin-1-one derivatives, characterized them by IR, MS, 1H NMR, and elemental analysis, and determined the crystal structure of 3-phenyl-11-(2-chloroph

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Synthesis of new 3-phenyl Substituted Dibenzo-1,4-diazepin-1-one Derivatives

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References

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Citations

Isophthaloylbis (Azanediyl) Dipeptide Ligand and Its Complexes: Structural Study, Spectroscopic, Molecular Orbital, Molecular Docking, and Biological Activity Properties

The dipeptide ligand H2L and its transition metal complexes show promising biological activity against Gram(+) and Gram() bacteria, with potential for antimicrobial applications.