Paper
Synthesis of 4-alkoxyaryl beta-D-glucopyranosides and their inhibitory effects on histamine release from rat peritoneal mast cells induced by concanavalin A.
Published Mar 15, 1994 · DOI · T. C. Wang, H. Furukawa, Y. Nihro
Chemical & pharmaceutical bulletin
6
Citations
0
Influential Citations
Abstract
The inhibitory effects of newly synthesized 4-alkoxyaryl beta-D-glucopyranosides on histamine release from rat peritoneal mast cells induced by concanavalin A were examined. A plot of hydrophobicity (k') against inhibitory activity of the compounds showed a distinct maximum, and 4-decyloxy-2,3,6-trimethylphenyl beta-D-glucopyranoside was the most potent inhibitor among the tested compounds.
4-alkoxyaryl beta-D-glucopyranosides effectively inhibit histamine release from rat peritoneal mast cells, with 4-decyloxy-2,3,6-trimethylphenyl beta-D-glucopyranoside being the most potent inhibitor.
Full text analysis coming soon...