Amino-1-methyl-3-n-propylpyrazole-5-carboxamide was prepared from 2-pentanone as a starting material. The synthetic route consists of Claisen condensation, cyclization, methylation, hydrolysis, nitration and reduction. The total yield was 46.8%, which was twice as high as the reported one.

This study demonstrates a novel synthetic route for 4-Amino-1-methyl-3-n-propylpyrazole-5-carboxamide, with a higher yield of 46.8% compared to previous reports.

Paper

Synthesis of 4-Amino-1-methyl-3-n-propylpyrazole-5-carboxamide

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