Convenient synthesis of 4-tert-butyl 2-ethyl 3-amino-1-benzyl-5-dialkylamino-1H-pyrrole-2,4-dicarboxylate derivatives

doi:10.1016/J.TET.2011.02.071

Paper

DOI: 10.1016/J.TET.2011.02.071

Convenient synthesis of 4-tert-butyl 2-ethyl 3-amino-1-benzyl-5-dialkylamino-1H-pyrrole-2,4-dicarboxylate derivatives

Published Apr 29, 2011 · Y. Nishio, Katsuya Uchiyama, M. Kito

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Abstract

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This novel synthetic method for 4-tert-butyl 2-ethyl 3-amino-1-benzyl-5-dialkylamino-1H-pyrrole-2,4-dicarboxylate derivatives allows for a highly selective synthesis without column chromatography purification.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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A novel, three-component reaction to the synthesis of 3-amino-4-cyano-5-aryl-1 H -pyrrole-2-carboxamides

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