Paper

Synthesis of 6-chloro-2-Aryl-1H-imidazo[4,5-b]pyridine derivatives: Antidiabetic, antioxidant, β-glucuronidase inhibiton and their molecular docking studies.

Published Apr 1, 2016 · DOI · M. Taha, N. Ismail, Syahrul Imran

Bioorganic chemistry

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Abstract

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In Vitro Study

Study Snapshot

6-chloro-2-aryl-1H-imidazo[4,5-b]pyridine derivatives show promising antiglycation, antioxidant, and -glucuronidase inhibitory activities, with compounds 3 and 4 showing significant inhibition compared to standard D-Saccharic acid 1,4-lactone

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis of 6-chloro-2-Aryl-1H-imidazo[4,5-b]pyridine derivatives: Antidiabetic, antioxidant, β-glucuronidase inhibiton and their molecular docking studies.

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