Paper
Synthesis of 6-Iodo-1-Tetralone
Published 2013 · Teng Da-wei
Chemistry & Bioengineering
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Abstract
6-Iodo-1-tetralone is an important intermediate for the synthesis of 5-HT6 receptor antagonist.It was synthesized from tetrahydronaphthalene,by the reaction of acetylation,oximation of carbonyl,Beckman rearrangement,oxidation and Sandmeyer reaction in five-steps with the total yield of 60%.
Study Snapshot
6-Iodo-1-tetralone can be synthesized from tetrahydronaphthalene in five-steps, providing an intermediate for the synthesis of 5-HT6 receptor antagonists.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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