Synthesis, absolute configuration and intermediates of 9-fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid (flumequine)

doi:10.1016/S0957-4166(99)00071-3

Paper

Synthesis, absolute configuration and intermediates of 9-fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid (flumequine)

Published Mar 26, 1999 · J. Bálint, Gabriella Egri, E. Fogassy

Tetrahedron-asymmetry

UNKNOWN SJR score

35

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Abstract

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Study Snapshot

Flumequine, an antibacterial agent, was synthesized from 6-fluoro-2-methyl-1,2,3,4-tetrahydroquinoline (FTHQ) and resolved with 3-bromocamphor-8-sulfonic acid, providing a new structural basis for its antibacterial properties.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis, absolute configuration and intermediates of 9-fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid (flumequine)

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