Paper
Synthesis and antimicrobial activities of novel 6-(1,3-thiazol-4-yl)-1,3-benzoxazol-2(3H)-one derivatives
Published Feb 1, 2014 · Krzysztof Z. Łączkowski, K. Misiura, Anna Biernasiuk
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Abstract
Abstract Synthesis, characterization and investigation of antimicrobial activities of seven new 6-(1,3-thiazol-4-yl)-1,3-benzoxazol-2(3H)-ones are presented. Their structures were determined using 1H NMR, 13C NMR and elemental analyses. The compounds possess some biological activity against Gram-positive bacteria, especially against Micrococcus luteus belonging to opportunistic pathogens, with an MIC of 31.25 μg/mL.
Novel 6-(1,3-thiazol-4-yl)-1,3-benzoxazol-2(3H)-one derivatives show some antimicrobial activity against Gram-positive bacteria, particularly Micrococcus luteus, with an MIC of 31.25 g/mL.
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