A series of 1,5-diphenyl-4-arylazopyrazoles was synthesized and evaluated for antimalarial activity. The compound possessing the best antimalarial activity of the entire study was 1,5-diphenyl-4-methoxyphenylazopyrazole. Another series of 5,5-dimethylcyclohexane-1,2,3-trione bishydrazones was prepared and tested as anthelmintics. No significant activity was observed.

1,5-diphenyl-4-methoxyphenylazopyrazole shows the best antimalarial activity, while 5,5-dimethylcyclohexane-1,2,3-trione bishydrazones show no significant anthelmintic activity.

Paper

Synthesis and biological activity of 1,5-diphenyl-4-arylazopyrazoles and 5,5-dimethylcyclohexane-1,2,3-trione bishydrazones.

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