Synthesis and antimicrobial activity of 2-fluorophenyl-4,6-disubstituted [1,3,5]triazines.

doi:10.1016/j.bmcl.2009.12.063

Paper

Synthesis and antimicrobial activity of 2-fluorophenyl-4,6-disubstituted [1,3,5]triazines.

Published Feb 1, 2010 · M. Saleh, S. Abbott, V. Perron

Bioorganic & medicinal chemistry letters

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58

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2

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Abstract

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In Vitro Study

Study Snapshot

2-fluorophenyl-4,6-disubstituted [1,3,5]triazines show significant antimicrobial activity against gram-positive bacteria and fungi, with the 3- or 4-fluorophenyl component being essential for activity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Synthesis and antimicrobial activity of 2-fluorophenyl-4,6-disubstituted [1,3,5]triazines.

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