Synthesis and microbiological activity of 5-methyl-2-[p-substituted phenyl]benzoxazoles

doi:10.1016/0223-5234(90)90137-R

Paper

DOI: 10.1016/0223-5234(90)90137-R

Synthesis and microbiological activity of 5-methyl-2-[p-substituted phenyl]benzoxazoles

Published Oct 1, 1990 · I. Yalcin, E. Şener, T. Özden

European Journal of Medicinal Chemistry

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Abstract

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In Vitro Study

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Study Snapshot

The 5-methyl-2-(p-substituted phenyl)benzoxazoles 7a-7g show broad spectrum antibacterial activity, with 7a-c and 7g showing significant activity against E coli and/or K pneumoniae at a 6.2 g/ml MIC.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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References

DOI: 10.7164/ANTIBIOTICS.37.441

The discovery, fermentation, isolation, and structure of antibiotic A33853 and its tetraacetyl derivative.

Antibiotic A33853, isolated from Streptomyces sp., NRRL 12068, has a unique structure containing an anhydride moiety, discovered through X-ray crystallographic study of its tetraacetyl derivative.

1984·27citations·K. Michel et al.·The Journal of antibiotics

The Journal of antibiotics

DOI: 10.1021/JM00216A011

Synthesis and antiinflammatory activity of some 2-aryl-6-benzoxazoleacetic acid derivatives.

Some 2-aryl-6-benzoxazoleacetic acid derivatives show antiinflammatory activity superior to phenylbutazone and similar to benoxaprofen.

1977·42citations·D. Dunwell et al.·Journal of medicinal chemistry

Journal of medicinal chemistry

DOI: 10.1021/JM00235A012

2-aryl-5-benzoxazolealkanoic acid derivatives with notable antiinflammatory activity.

5-substituted 2-arylbenzoxazoles show significant antiinflammatory activity, with compounds like 2-(4-chlorophenyl)-alpha-methyl-5-benzoxazoleacetic acid showing three to five times more activity than phenylbutazone.

1975·46citations·D. Dunwell et al.·Journal of medicinal chemistry

Journal of medicinal chemistry

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DOI: 10.1016/j.molstruc.2020.128244

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