Synthesis and antiangiogenic activity of 6-amido-2,4,5-trimethylpyridin-3-ols.

doi:10.1016/j.bmcl.2014.05.005

Paper

Synthesis and antiangiogenic activity of 6-amido-2,4,5-trimethylpyridin-3-ols.

Published Jul 15, 2014 · Hyunji Lee, S. Banskota, Dong-Guk Kim

Bioorganic & medicinal chemistry letters

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14

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0

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Abstract

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In Vitro Study

Study Snapshot

6-amido-2,4,5-trimethylpyridin-3-ols show up to several fold-higher antiangiogenic activities and better antitumor effects than SU4312, offering potential for novel angiogenesis inhibitors.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and antiangiogenic activity of 6-amido-2,4,5-trimethylpyridin-3-ols.

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