Synthesis and in vitro antimycobacterial activity of balofloxacin ethylene isatin derivatives.

doi:10.1016/j.ejmech.2010.04.027

Paper

DOI: 10.1016/j.ejmech.2010.04.027

Synthesis and in vitro antimycobacterial activity of balofloxacin ethylene isatin derivatives.

Published Aug 1, 2010 · Lian-Shun Feng, Mingliang Liu, Bo Wang

European journal of medicinal chemistry

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

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Balofloxacin ethylene isatin derivatives with improved lipophilicity show potential as new antimycobacterial agents, with compound 3h being 32 fold more potent than balofloxacin against MTB 09710 and MTB H37Rv ATCC 27294.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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