Synthesis and analgesic activity of methyl-1-(1-aryl-3-arylamino-3-oxo-2-cyanopropyl)cyclohexane carboxylates

doi:10.1007/s11094-012-0844-7

Paper

Synthesis and analgesic activity of methyl-1-(1-aryl-3-arylamino-3-oxo-2-cyanopropyl)cyclohexane carboxylates

Published Dec 1, 2012 · N. F. Kirillov, R. R. Makhmudov, E. A. Nikiforova

Pharmaceutical Chemistry Journal

Q4 SJR score

0

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Methyl-1-(1-aryl-3-arylamino-3-oxo-2-cyanopropyl)cyclohexane carboxylates were prepared by reaction of methyl-1-bromocyclohexane carboxylates with zinc and arylamides of 3-aryl-2-cyanopropenoic acids. The synthesized compounds possessed analgesic activity and had low toxicity.

Study Snapshot

Methyl-1-(1-aryl-3-arylamino-3-oxo-2-cyanopropyl)cyclohexane carboxylates show analgesic activity and low toxicity, making them potential candidates for pharmaceutical applications.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Synthesis and analgesic activity of methyl-1-(1-aryl-3-arylamino-3-oxo-2-cyanopropyl)cyclohexane carboxylates

Sign up to use Study Snapshot

References

Citations