Synthesis, antioxidant and antimicrobial activity of novel vanillin derived piperidin-4-one oxime esters: preponderant role of the phenyl ester substituents on the piperidin-4-one oxime core.

doi:10.1016/j.bmcl.2012.10.019

Paper

Synthesis, antioxidant and antimicrobial activity of novel vanillin derived piperidin-4-one oxime esters: preponderant role of the phenyl ester substituents on the piperidin-4-one oxime core.

Published Dec 15, 2012 · S. T. Harini, H. V. Kumar, J. Rangaswamy

Bioorganic & medicinal chemistry letters

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79

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Abstract

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Study Snapshot

Phenyl ester substituents in vanillin-derived piperidin-4-one oxime esters enhance their antioxidant and antimicrobial properties, with compounds 5i and 5j outperforming standard antioxidants.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis, antioxidant and antimicrobial activity of novel vanillin derived piperidin-4-one oxime esters: preponderant role of the phenyl ester substituents on the piperidin-4-one oxime core.

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