Paper
Synthesis and biological activity of structurally diverse phthalazine derivatives: A systematic review.
Published Sep 15, 2019 · J. Sangshetti, Shahebaaz K. Pathan, R. Patil
Bioorganic & medicinal chemistry
Q2 SJR score
28
Citations
0
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Systematic ReviewStudy Snapshot
Phthalazine derivatives show potential as pharmacological scaffolds for novel drugs with diverse pharmacological activities, including antidiabetic, anticancer, antihypertensive, and antithrombotic properties.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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Citations
Phthalazine based hydrazone as potent radical scavenger: Synthesis, spectral characterization, single crystal X-ray diffraction, DFT studies, molecular docking, ADME, antioxidant and antimicrobial activity of (E)-1-(2-substitutedbenzylidene)phthalazine derivatives
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Novel hybrid compounds containing phthalazin-1(2H)-imine and 4,5-dihydro-1H-imidazole cores show potential biological activities, but show no antiproliferative activity against cancer cell lines.
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