Synthesis and anti-microbial activity of some 1- substituted amino-4,6-dimethyl-2-oxo-pyridine-3-carbonitrile derivatives.

doi:10.1016/j.ejmech.2011.08.018

Paper

Synthesis and anti-microbial activity of some 1- substituted amino-4,6-dimethyl-2-oxo-pyridine-3-carbonitrile derivatives.

Published Oct 1, 2011 · Rizk E. Khidre, A. Abu‐Hashem, M. El‐Shazly

European journal of medicinal chemistry

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73

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2

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Abstract

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Study Snapshot

Most of the synthesized 1-substituted amino-4,6-dimethyl-2-oxo-pyridine-3-carbonitrile derivatives exhibit both antibacterial and antifungal activities, with compounds 8a and 8b showing comparable effects to well-known agents.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and anti-microbial activity of some 1- substituted amino-4,6-dimethyl-2-oxo-pyridine-3-carbonitrile derivatives.

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