Paper

Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids.

Published Apr 8, 2020 · Priti Singh, B. Swain, Pavitra S Thacker

Bioorganic chemistry

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Abstract

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In Vitro Study

Study Snapshot

These indolylchalcone-benzenesulfonamide-1,2,3-triazole hybrids show potential as hCA I-selective inhibitors with inhibition constants in the nanomolar range.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids.

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