Eight(Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino) acetate derivatives(six of them were new derivatives) were synthesized from methyl(ethyl) acetoacetates,aldehydes and acyl chlorides.The structures were characterized by 1H NMR,IR and MS.The preliminary bioassays tests results showed that all derivatives exhibited certain antibacterial activities against Fusarium graminearum and Fusarium solani in 200 mg·L-1.

Novel (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino) acetate derivatives show promising antibacterial activity against Fusarium graminearum and Fusarium solani at 200 mg/L.

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Synthesis and Antibacterial Activity of Novel (Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)Acetate Derivatives

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