Synthesis and Antibacterial Activity of 2-(2-(Cyclopropylmethoxy)Phenyl)-5-Methyl-1,3,4- Oxadiazole

doi:10.13005/ojc/330355

Paper

Synthesis and Antibacterial Activity of 2-(2-(Cyclopropylmethoxy)Phenyl)-5-Methyl-1,3,4- Oxadiazole

Published Jun 20, 2017 · A. Parameshwar, V. Selvam, M. Ghashang

Oriental journal of chemistry

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2

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1

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Abstract

Heterocyclic compounds containing the five-membered oxadiazole nucleus possess verity of biological activities. 1,3,4oxadiazole moieties are important because of their versatile biological action. The present study depicts synthesis of some novel 2-(2-(cyclopropylmethoxy)phenyl)-5methyl-1,3,4oxadiazole was prepared from N’-acetyl-2-(cyclopropylmethoxy)benzohydrazide by using triphenylphosphine, triethylamine, carbon tetrachloride and acetonitrile at 100°C for 1h. The final compound was examined for its antibacterial activity.

Study Snapshot

The novel compound 2-(2-(cyclopropylmethoxy)phenyl)-5-methyl-1,3,4-oxadiazole shows promising antibacterial activity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Synthesis and Antibacterial Activity of 2-(2-(Cyclopropylmethoxy)Phenyl)-5-Methyl-1,3,4- Oxadiazole

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