Paper
Synthesis and Anticancer Activity of 1,3,4-Oxadiazole-oxazolo[4,5-b]pyridine Derivatives
Published Jul 1, 2020 · Suresh Babu Kokkiligadda, Sivanadh Musunuri, B. Maiti
Russian Journal of General Chemistry
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Abstract
A number of 1,3,4-oxadiazole incorporated oxazolo[4,5-b]pyridine derivatives has been synthesized, characterized and tested for anticancer activity against four human cancer cell lines including breast cancer (MCF-7), lung cancer (A549), colon cancer (Colo-205), and ovarian cancer (A2780) using etoposide as a standard drug. All products demonstrate good anticancer activity, several compounds can be considered as promising anticancer agents.
1,3,4-oxadiazole-oxazolo[4,5-b]pyridine derivatives show promising anticancer activity against breast, lung, colon, and ovarian cancer cell lines.
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