Synthesis and Anticoccidial Activity of ethyl 6-substitutedbenzyloxy-7-alkoxy-4-hydroxyquinoline-3-carboxylates

doi:10.3184/030823409X439726

Paper

Synthesis and Anticoccidial Activity of ethyl 6-substitutedbenzyloxy-7-alkoxy-4-hydroxyquinoline-3-carboxylates

Published Apr 1, 2009 · Y. Zou, Chun-Rong Yan, Yabiao Weng

Journal of Chemical Research

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Abstract

A series of novel ethyl 6-substitutedbenzyloxy-7-alkoxy-4-hydroxyquinoline-3-carboxylates have been designed and synthesised from 4-nitro-2-alkoxyphenol. Their structures have been characterised by 1H NMR, HRMS and IR spectra. Anticoccidial activities of these compounds were evaluated according to the ACI (the anticoccidial index) method. The results indicated that three of the tested compounds exhibited anticoccidial activities against Eimeria tenella in chicken feed with a dose of 27 mg/kg.

Non-RCT

Animal Study

Study Snapshot

Three novel ethyl 6-substitutedbenzyloxy-7-alkoxy-4-hydroxyquinoline-3-carboxylates show anticoccidial activities against Eimeria tenella in chicken feed at a dose of 27 mg/kg.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Paper

Synthesis and Anticoccidial Activity of ethyl 6-substitutedbenzyloxy-7-alkoxy-4-hydroxyquinoline-3-carboxylates

References

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Citations