Synthesis and anti-CVB3 activity of 4-amino acid derivative substituted pyrimidine nucleoside analogues.

doi:10.1016/j.bmcl.2019.126770

Paper

Synthesis and anti-CVB3 activity of 4-amino acid derivative substituted pyrimidine nucleoside analogues.

Published Oct 28, 2019 · Le-Fu Tao, Yujiang Li, Xiao-he Guo

Bioorganic & medicinal chemistry letters

Q2 SJR score

10

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1

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Abstract

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In Vitro Study

Study Snapshot

4-amino acid derivative substituted pyrimidine nucleoside analogues show potent anti-CVB3 activity, with compound 2 showing similar cytotoxicity to ribavirin.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and anti-CVB3 activity of 4-amino acid derivative substituted pyrimidine nucleoside analogues.

References

Citations