Synthesis and anti-inflammatory activity of some new 1,3,4-thiadiazoles containing pyrazole and pyrrole nucleus

doi:10.1016/J.JSCS.2012.11.007

Paper

Synthesis and anti-inflammatory activity of some new 1,3,4-thiadiazoles containing pyrazole and pyrrole nucleus

Published Sep 1, 2016 · S. Maddila, S. Gorle, C. Sampath

Journal of Saudi Chemical Society

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Abstract

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In Vitro Study

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New 1,3,4-thiadiazole compounds with pyrazole-3-carboxamides and pyrrole-3-carboxamides show significant anti-inflammatory activity, with compounds 3c, 3d, and 4c showing potent activity compared to standard drug indomethacin.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Synthesis and anti-inflammatory activity of some new 1,3,4-thiadiazoles containing pyrazole and pyrrole nucleus

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