Synthesis and antiinflammatory activity of some new 1,3,5-trisubstituted pyrazolines bearing benzene sulfonamide.

doi:10.1016/j.bmcl.2008.10.105

Paper

Synthesis and antiinflammatory activity of some new 1,3,5-trisubstituted pyrazolines bearing benzene sulfonamide.

Published 2009 · I. G. Rathish, K. Javed, Shamim Ahmad

Bioorganic & medicinal chemistry letters

Q2 SJR score

141

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1

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Highly Cited

Study Snapshot

New 1,3,5-trisubstituted pyrazolines bearing benzene sulfonamide derivatives show anti-inflammatory activity and COX-1 and COX-2 inhibitory activity, with compounds 3k, 3l, and 3m showing more potent activity than celecoxib.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and antiinflammatory activity of some new 1,3,5-trisubstituted pyrazolines bearing benzene sulfonamide.

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