Synthesis and antiprotozoal activity of novel 2-{[2-(1H-imidazol-1-yl)ethyl]sulfanyl}-1H-benzimidazole derivatives.

doi:10.1016/j.bmcl.2013.05.012

Paper

DOI: 10.1016/j.bmcl.2013.05.012

Synthesis and antiprotozoal activity of novel 2-{[2-(1H-imidazol-1-yl)ethyl]sulfanyl}-1H-benzimidazole derivatives.

Published Jul 15, 2013 · J. Pérez‐Villanueva, A. Hernández-Campos, L. Yépez-Mulia

Bioorganic & medicinal chemistry letters

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Abstract

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In Vitro Study

Study Snapshot

Novel 2-[2-(1H-imidazol-1-yl)ethyl]sulfanyl-1H-benzimidazole derivatives show strong antiprotozoal activity, even better than metronidazole, against protozoa Trichomonas vaginalis

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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