Synthesis and anti-tumor activity of 2-amino-3-cyano-6-(1H-indol-3-yl)-4-phenylpyridine derivatives in vitro.

doi:10.1016/j.ejmech.2011.03.055

Paper

Synthesis and anti-tumor activity of 2-amino-3-cyano-6-(1H-indol-3-yl)-4-phenylpyridine derivatives in vitro.

Published Jul 1, 2011 · Fan Zhang, Yanfang Zhao, Li Sun

European journal of medicinal chemistry

Q2 SJR score

105

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1

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Abstract

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In Vitro Study

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Study Snapshot

Novel 2-amino-3-cyano-6-(1H-indol-3-yl)-4-phenylpyridine derivatives show excellent anti-tumor activity against various cancer cell lines, with compound 27 showing the most promising activity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and anti-tumor activity of 2-amino-3-cyano-6-(1H-indol-3-yl)-4-phenylpyridine derivatives in vitro.

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