Paper
Synthesis of 3-(4-fluorophenyl)-3-(4-methoxyphenyl)-1-propanarylamines and their antibacterial activity
Published Aug 2, 2017 · N. Arutyunyan, L. A. Akopyan, R. A. Akopyan
Russian Journal of General Chemistry
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Abstract
Condensation of 3-(4-fluorophenyl)-3-(4-methoxyphenyl)-1-propanamine with aromatic aldehydes and ketones followed by the reduction of the obtained azomethines with NaBH4 afforded secondary propanaryl -amines, whose oxalates and hydrochlorides possess high antibacterial activity.
Secondary propanaryl -amines, synthesized by condensing 3-(4-fluorophenyl)-3-(4-methoxyphenyl)-1-propanamine with aromatic aldehydes and ketones, exhibit high antibacterial activity.
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