Synthesis and bioactivity of novel sulfone derivatives containing 2,4-dichlorophenyl substituted 1,3,4-oxadiazole/thiadiazole moiety as chitinase inhibitors

doi:10.1016/J.PESTBP.2011.05.006

Paper

Synthesis and bioactivity of novel sulfone derivatives containing 2,4-dichlorophenyl substituted 1,3,4-oxadiazole/thiadiazole moiety as chitinase inhibitors

Published Sep 1, 2011 · Weiming Xu, Song Yang, Pinaki S. Bhadury

Pesticide Biochemistry and Physiology

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70

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Abstract

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In Vitro Study

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Study Snapshot

Novel sulfone derivatives with 2,4-dichlorophenyl substituted 1,3,4-oxadiazole/thiadiazole moiety show moderate to good antifungal activity, particularly inhibiting mycelia growth by 50% against nine types of fungi.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and bioactivity of novel sulfone derivatives containing 2,4-dichlorophenyl substituted 1,3,4-oxadiazole/thiadiazole moiety as chitinase inhibitors

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