Synthesis and biodistribution of 123I N-(2-aminoethyl)-5-iodo-2-pyridinecarboxamide (Ro 43-0463), a monoamine oxidase B inhibitor.

doi:10.1016/0883-2897(91)90119-6

Paper

Synthesis and biodistribution of 123I N-(2-aminoethyl)-5-iodo-2-pyridinecarboxamide (Ro 43-0463), a monoamine oxidase B inhibitor.

Published 1991 · S. E. Macwhorter, R. Baldwin

International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Study Snapshot

The radioligand 123I N-(2-aminoethyl)-5-iodo-2-pyridinecarboxamide (Ro 43-0463) shows peak brain uptake of 0.50% at 30 minutes and slow washout over 60 minutes in rats.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and biodistribution of 123I N-(2-aminoethyl)-5-iodo-2-pyridinecarboxamide (Ro 43-0463), a monoamine oxidase B inhibitor.

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