A series of new 1-(substituted-pyrazole-4-carbonyl)-pyrazoles were synthesized by the reaction of 5-amino-1-methyl-3-(methylthio)-1H-pyrazole-4-carbohydrazide and 5-amino-1-methyl-1H-pyrazole-4-carbohydrazide respectively with 2-cyano-3,3-bis(alkylthio) acrylates or 2-\malononitriles. All the compounds were structurally confirmed by elemental analysis and 1H NMR. Their herbicidal activities were tested. Bioassay results showed that some of them had herbicidal activities. The structure-activity relationship was discussed, which indicated the substituents on the pyrazole ring have influence on the title compounds activities.

Novel 1-(substituted-pyrazole-4-carbonyl)-pyrazoles show some herbicidal activities, with substituents on the pyrazole ring influencing their activities.

Paper

Synthesis and Biological Activity of Novel 1-(Substituted-pyrazole-4-carbonyl) Pyrazoles

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