Synthesis, Characterisation and Antimicrobial Activity of Novel 2-alkoxycarbonylamino-1,3,2-benzodiazaphosphole 2-oxides

doi:10.3184/030823409X393655

Paper

Synthesis, Characterisation and Antimicrobial Activity of Novel 2-alkoxycarbonylamino-1,3,2-benzodiazaphosphole 2-oxides

Published Feb 1, 2009 · P. V. G. Reddy, A. Krishna, M. V. N. Reddy

Journal of Chemical Research

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Abstract

A series of some new class of 2-alkoxycarbonylamino-1,3,2-benzodiazaphosphole 2-oxides 4a–j were synthesised by reacting 3,4-diaminobenzophenone (3) with various dichlorophosphinyl carbamates (2) in dry toluene-tetrahydrofuran mixture (1:1) in the presence of triethylamine at 45–50°C. All the title compounds were evaluated for antimicrobial activity to determine their efficacy and were effective in suppressing the growth of bacteria and fungi. The chemical structures of the title products were characterised by IR, 1H, 13C and 31P NMR and mass spectral studies.

Study Snapshot

Novel 2-alkoxycarbonylamino-1,3,2-benzodiazaphosphole 2-oxides effectively suppress the growth of bacteria and fungi, offering potential as antimicrobial agents.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Paper

Synthesis, Characterisation and Antimicrobial Activity of Novel 2-alkoxycarbonylamino-1,3,2-benzodiazaphosphole 2-oxides

References

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5-Methoxy-a-tetralones can be used for the synthesis of diterpenes, sesquiterpenes, and other natural products, with potential applications in pharmaceutical and biotechnology industries.

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Organophosphorus chemistry is a complex field with applications in biology, agriculture, and technology.

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This book provides an in-depth understanding of the infrared spectra of organophosphorus compounds, aiding in the identification and quantification of these compounds.

Citations

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