N-(4-bromobenzylidene)-2,3-dihydrobenzo[b][1,4]dioxin-6-amine: Synthesis, crystal structure, docking and in-vitro inhibition of PLA2

doi:10.1016/j.molstruc.2020.128441

Paper

N-(4-bromobenzylidene)-2,3-dihydrobenzo[b][1,4]dioxin-6-amine: Synthesis, crystal structure, docking and in-vitro inhibition of PLA2

Published Oct 15, 2020 · M. Hema, R. R. Arun Renganathan, S. Nanjundaswamy

Journal of Molecular Structure

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9

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Abstract

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In Vitro Study

Study Snapshot

The novel compound N-(4-bromobenzylidene)-2,3-dihydrobenzo[b][1,4]dioxin-6-amine shows good inhibition against sPLA2 enzyme, with potential anti-inflammatory activity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

N-(4-bromobenzylidene)-2,3-dihydrobenzo[b][1,4]dioxin-6-amine: Synthesis, crystal structure, docking and in-vitro inhibition of PLA2

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