Paper
Synthesis of derivatives of 2-amino-4-p-chlorophenylthiazole-5-acetic acid.
Published 1978 · T. Jakóbiec, J. Stankiewicz, R. Dobek
Archivum immunologiae et therapiae experimentalis
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Abstract
In the course of studies on compounds with expected antiinflammatory and immunosuppressive action a number of new derivatives of 2-amino-4-p-chlorophenylthiazole-s-acetic acid have been synthetized. The chemical structure of these compounds has been confirmed by elemental analysis and IR spectra. The newly obtained compounds were investigated pharmacologically. It has been found that some of the derivatives possess antiinflammatory and immunosuppressive activity.
New derivatives of 2-amino-4-p-chlorophenylthiazole-5-acetic acid show potential antiinflammatory and immunosuppressive properties.
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