Enantioselective synthesis of both enantiomers of vicinal norbornanediamines through the Leuckart reaction of 2-norbornanones

doi:10.1016/S0957-4166(01)00376-7

Paper

Enantioselective synthesis of both enantiomers of vicinal norbornanediamines through the Leuckart reaction of 2-norbornanones

Published Aug 29, 2001 · A. Martínez, E. T. Vilar, A. Fraile

Tetrahedron-asymmetry

UNKNOWN SJR score

4

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Abstract

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Study Snapshot

The Leuckart reaction of 2-norbornanones with formamide and formic acid produces enantiomerically pure 1,2-norbornane diamides, useful for chiral vicinal diamines in medicinal chemistry and asymmetric synthesis.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Enantioselective synthesis of both enantiomers of vicinal norbornanediamines through the Leuckart reaction of 2-norbornanones

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