Paper
Synthesis of Ethyl 1-Ethyl-6-fluoro-1,4-dihydro-8-hydroxy-4-oxoquinoline-3-carboxylate
Published 1994 · S. Rádl
Collection of Czechoslovak Chemical Communications
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3
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Abstract
In connection with our research into antibacterial fluoroquinolones we required ethyl 1-ethyl-6-fluoro-1,4-dihydro-8-hydroxy-4-oxoquinoline-3-carboxylate ( IIc ) as an intermediate. This paper describes synthesis of this compound and the corresponding carboxylic acid.
Study Snapshot
This study presents a method for synthesizing ethyl 1-ethyl-6-fluoro-1,4-dihydro-8-hydroxy-4-oxoquinoline-3-carboxylate (IIc) and its corresponding carboxylic acid, which is useful in antibacterial
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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