Synthesis of ethyl 3-phenyl-4-(trifluoromethyl)isoxazole-5-carboxylate via regioselective dipolar cycloaddition

doi:10.1016/J.TETLET.2012.05.089

Paper

Synthesis of ethyl 3-phenyl-4-(trifluoromethyl)isoxazole-5-carboxylate via regioselective dipolar cycloaddition

Published Aug 1, 2012 · Michael A. Schmidt, K. Katipally, Antonio Ramirez

Tetrahedron Letters

Q3 SJR score

16

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Abstract

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Study Snapshot

This study successfully synthesized ethyl 3-phenyl-4-(trifluoromethyl)isoxazole-5-carboxylate using regioselective 1,3-dipolar cycloaddition between phenyl nitrile oxide and various 4,4,4

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis of ethyl 3-phenyl-4-(trifluoromethyl)isoxazole-5-carboxylate via regioselective dipolar cycloaddition

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