Paper

Synthesis and evaluation of 2-[2-(phenylthiomethyl)-1H-benzo[d] imidazol-1-yl)acetohydrazide derivatives as antitumor agents.

Published May 1, 2012 · Ting Liu, Changyan Sun, Xiumei Xing

Bioorganic & medicinal chemistry letters

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Abstract

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Study Snapshot

Acetylhydrazone derivatives containing 2-(phenylthiomethyl)-1H-benzo[d]-imidazole moieties show excellent antitumor activity against various cancer cells, with IC50 values ranging from 4-17 M.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis and evaluation of 2-[2-(phenylthiomethyl)-1H-benzo[d] imidazol-1-yl)acetohydrazide derivatives as antitumor agents.

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